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PhD Awarded

The first Paul Ehrlich MedChem Euro-PhD certificate was awarded in 2012 at the Network meeting in Ljubljana and since then altogether 42 certificates were awarded to superb doctoral students who obtained their national PhD degree in medicinal chemistry.
PhDs awarded are listed by year meeting.

XI Meeting of the Paul Ehrlich Euro-PhD Network - #PEVM2022, July 14th-16th, 2022 - Barcelona

Barreca, Marilia

University of Palermo (Italy)

     
  BarrecaMarilia   Title of the PhD thesis: [1,2]oxazole derivatives: synthesis and biological evaluation against multiple malignant cell types  
    Year of PhD dissertation: 2021  
    Name of Supervisor: Prof. Paola BArraja  
    International hosting institution: Institute of Oncology Research (IOR), Bellinzona
(Switzerland)
 
    Name of the host supervisor: Prof. Francesco Bertoni  

Coricello, Adriana

Universita' degli Studi 'Magna Graecia' di Catanzaro (Italy)

     
  CoricelloAdriana   Title of the PhD thesis: Natural products in drug discovery. In silico approaches for the detection of new hits against unexplored molecular targets  
    Year of PhD dissertation: 2022  
    Name of Supervisor: Prof. Stefano Alcaro  
    International hosting institution: Cardiff University
(Galles)
 
    Name of the host supervisor: Prof. Nigel Richards  

Mirabile, Salvatore

University of Messina (Italy)

     
  MirabileSalvatore   Title of the PhD thesis: Structure- and Ligand-based Optimization of Fragment Binding Tyrosinase from Agaricus bisporus to Develop Anti-Melanogenic Agents  
    Year of PhD dissertation: 2022  
    Name of Supervisor: Prof. Rosaria Gitto  
    International hosting institution: University of Vienna
(Austria)
 
    Name of the host supervisor: Prof. Vittorio Pace  

Nizi, Maria Giulia

University of Perugia (Italy)

     
  NiziMariaGiulia   Title of the PhD thesis: Discovery of potent and selective PARP inhibitors as valuable pharmacological tools and next generation anticancer agents  
    Year of PhD dissertation: 2022  
    Name of Supervisor: Prof. Oriana Tabarrini  
    International hosting institution: University of Oulu
(Finland)
 
    Name of the host supervisor: Prof. Lari Lehtio  

Rullo, Mariagrazia

University of Bari "Aldo Moro" (Italy)

     
  RulloMariagrazia   Title of the PhD thesis: Development of MAO-B centered Multitarget ligands against Neurodegenerative Disorders  
    Year of PhD dissertation: 2022  
    Name of Supervisor: Prof. Cosimo Damiano Altomare  
    International hosting institution: University of Umea (Sweden)  
    Name of the host supervisor: Prof. Anna Linusson  

Paul Ehrlich Euro-PhD Network Virtual Meeting 2021 - #PEVM2021, July 26th-28th, 2021th-16th, 2022

Ambrosio, Francesca Alessandra

Universita' degli Studi 'Magna Graecia' di Catanzaro (Italy)

     
  AmbrosioFrancesca   Title of the PhD thesis: Molecular Modeling studies on antiviral targets: drug resistance mechanisms and rational drug design  
    Year of PhD dissertation: 2019  
    Name of Supervisor: Prof. Anna Artese  
    International hosting institution: Scripps Research Institute
La Jolla, CA (USA)
 
    Name of the host supervisor: Prof. Stefano Forli  

Bouz, Ghada

Charles University (Czech Republic)

     
  Bouz, Ghada   Title of the PhD thesis: Pyrazinecarboxamide derivatives as potential antimicrobials  
    Year of PhD dissertation: 2020  
    Name of Supervisor: Prof. Martin Dolezal  
    International hosting institution: San Pablo University (CEU) Madrid (Spain)  
    Name of the host supervisor: Prof. Ana Ramos  

Ceramella, Jessica

University of Calabria (Italy)

     
  CeramellaJessica   Title of the PhD thesis: Design and biological evaluation of new anticancer agents vehicled in innovative pharmaceutical matrices  
    Year of PhD dissertation: 2020  
    Name of Supervisor: Prof. Maria Stefania Sinicropi
and Prof. Domenico Gabriele
 
    International hosting institution: Centre d'etudes et de recherche sur le medicament de Normandie (CERMN),
Universite' de Caen Normandie (France)
 
    Name of the host supervisor: Prof. Aurelie Malzert-Freon
and Dr. Anne-Claire Groo
 

Chavarria, Daniel

University of Porto (Portugal)

     
  ChavarriaDaniel   Title of the PhD thesis: Development of new chemical entities based on natural scaffolds with therapeutic potential towards age related disorders  
    Year of PhD dissertation: 2020  
    Name of Supervisor: Prof. Maria Fernanda Martins Borges  
    International hosting institution: Faculty of Pharmacy of the University of Santiago de Compostela  
    Name of the host supervisor: Prof. Dr. Eugenio Uriarte Villares  

Di Geronimo Quintero, Bruno

Universidad San Pablo-CEU (Spain)

     
  DiGeronimoQuinteroBruno   Title of the PhD thesis: Computer-aided Drug Design based on Phosphatases (PTPRZ, PTPRGamma, PTP1B), Kinases (CK2)and Histone Deacetylases (HDAC1, HDAC6) as drug targets  
    Year of PhD dissertation: 2020  
    Name of Supervisor: Prof. Beatriz de Pascual-Teresa Fernandez  
    International hosting institution: Institute of Organic Chemistry and Biochemistry (IOCB), Prague (Czech Republic)  
    Name of the host supervisor: Dr. Lubomir Rulisek  

Mancuso, Francesca

University of Messina (Italy)

     
  MancusoFrancesca   Title of the PhD thesis: Targeting Carbonic Anhydrases (CAs): Rational Design, Synthesis, Structural Studies and Biochemical Evaluation  
    Year of PhD dissertation: 2021  
    Name of Supervisor: Prof. Rosaria Gitto  
    International hosting institution: Institute of Organic Chemistry and Biochemistry of the CAS, Prague (Czech Republic)  
    Name of the host supervisor: Dr. Milan Vrabel  

Marin, Javier Garcia

Universidad de Alcala' (Spain)

     
  MarinJavierGarcia   Title of the PhD thesis: Strategies against chronic kidney disease: new modulators of PTP1B and ILK  
    Year of PhD dissertation: 2020  
    Name of Supervisor: Prof. Juan Jose' Vaquero
and Prof. Ramon Alajarin
 
    International hosting institution: School of Chemistry, Department of Theoretical Chemistry, University of Bristol (UK)  
    Name of the host supervisor: Prof. Adrian J. Mulholland  

Mesiti, Francesco

Universita' degli Studi 'Magna Graecia' di Catanzaro (Italy)

     
  MesitiFrancesco   Title of the PhD thesis: Mapping the chromone-3-phenylcarboxamide pharmacophore: structure-activity-toxicity and efflux trasport studies  
    Year of PhD dissertation: 2020  
    Name of Supervisor: Prof. Stefano Alcaro  
    International hosting institution: FCUP Faculdade de Ciencia, Universidade do Porto (Portugal)  
    Name of the host supervisor: Prof. Maria Fernanda Martins Borges  

Szczepanska, Katarzyna

Jagiellonian University Medical College (Poland)

     
  SzczepanskaKatarzyna   Title of the PhD thesis: The search for novel histamine H3 receptor ligands in the group of piperazine derivatives  
    Year of PhD dissertation: 2020  
    Name of Supervisor: Prof. Katarzyna Kiec-Kononowicz  
    International hosting institution: University of Regensburg (Germany)  
    Name of the host supervisor: Prof. Steffen Pockes  

Vittorio, Serena

University of Messina (Italy)

     
  VittorioSerena   Title of the PhD thesis: Study and design of modulators of protein-protein interactions implicated in tumor and neurodegenerative diseases  
    Year of PhD dissertation: 2021  
    Name of Supervisor: Prof. Laura De Luca  
    International hosting institution: University of Vienna (Austria)  
    Name of the host supervisor: Prof. Thierry Langer  




9th Meeting of the Paul Ehrlich MedChem Euro-PhD Network, 13-15 June 2019, Catanzaro (Italy)

Bagetta, Donatella

Universita' degli Studi 'Magna Graecia' di Catanzaro (Italy)

     
  Donatella Bagetta   Title of the PhD thesis: Computational studies on MAO-B and AChE inhibitors as potential anti-Parkinson's and anti-Alzheimer's agents  
    Year of PhD dissertation: 2019  
    Name of Supervisor: Prof. Francesco Ortuso  
    International hosting institution: University of Vienna (Austria)  
    Name of the host supervisor: Prof. Thierry Langer  


Benfeito, Sofia

University of Porto (Portugal)

     
  Benfeito, Sofia   Title of the PhD thesis: Design and development of multi-target agents for neurodegenerative diseases  
    Year of PhD dissertation: 2019  
    Name of Supervisor: Prof. Fernanda Borges  
    International hosting institution: Faculty of Pharmacy of Santiago de Compostela (Spain)  
    Name of the host supervisor: Prof. Eugenio Uriarte  


Felicetti, Tommaso

University of Perugia (Italy)

     
  Felicetti, Tommaso   Title of the PhD thesis: Quinoline-based efflux inhibitors as antimicrobial resistance breakers (ARB)  
    Year of PhD dissertation: 2019  
    Name of Supervisor: Prof. Violetta Cecchetti and Prof. Stefano Sabatini  
    International hosting institution: University of Groningen (Netherlands)  
    Name of the host supervisor: Prof. Anna K.H. Hirsch  


Fernandes, Carlos

University of Porto (Portugal)

     
  Fernandes Carlos   Title of the PhD thesis: Development of PEGylated platforms to overcome blood-brain barrier constraints in neurodegenerative therapy  
    Year of PhD dissertation: 2019  
    Name of Supervisor: Prof. Fernanda Borges  
    International hosting institution: Faculty of Pharmacy of Santiago de Compostela (Spain)  
    Name of the host supervisor: Prof. Eugenio Uriarte  


Ielo, Laura

University of Messina (Italy)

     
  Ielo Laura   Title of the PhD thesis: Identification of New Tyrosinase Inhibitors via Computational Studies, Synthesis and Structural Characterization  
    Year of PhD dissertation: 2019  
    Name of Supervisor: Prof. Laura De Luca  
    International hosting institution: University of Vienna (Austria)  
    Name of the host supervisor: Prof. Vittorio Pace  


Lupia, Antonio

Universita' degli Studi 'Magna Graecia' di Catanzaro (Italy)

     
  Lupia Antonio   Title of the PhD thesis: Molecular modelling of the epitopes recognized by neoplastic B-cells in Chronic Lymphocytic Leukemia  
    Year of PhD dissertation: 2019  
    Name of Supervisor: Prof. Ileana Quinto  
    International hosting institution: Institute of Oncology Research - IOR, Bellinzona (Switzerland)  
    Name of the host supervisor: Dr. Eugenio Gaudio  


8th Meeting of the Paul Ehrlich MedChem Euro-PhD Network, 12-14 July 2018, Porto (Portugal)

Astolfi, Andrea

University of Perugia (Italy)

     
  Astolfi Andrea   Title of the PhD thesis: Computational Modeling and Inhibitor Design of p38 MAPK  
    Year of PhD dissertation: 2018  
    Name of Supervisor: Prof. Maria Letizia Barreca and Prof. Violetta Cecchetti  
    International hosting institution: Institute of Structural and Molecular Biology, London (UK)  
    Name of the host supervisor: Prof. Francesco Luigi Gervasio, PhD  


Castoldi, Laura

University of Vienna (Austria)

     
  Castoldi Laura   Title of the PhD thesis: Organic Synthesis with Lithium Carbenoids at the Helm: Mechanistic Aspects and Applications in Synthetic Medicinal Chemistry  
    Year of PhD dissertation: 2018  
    Name of Supervisor: Dr. Vittorio Pace and Prof. Wolfgang Holzer  
    International hosting institution: Complutense University of Madrid (Spain)  
    Name of the host supervisor: Prof. Andres R Alcantara, PhD  


Oliveira, Ana Catarina Gomes

University of Porto (Portugal)

     
  Oliveira Ana Catarina   Title of the PhD thesis: Benzoic acid as a valid scaffold for the development of dual- target directed drugs for Alzheimer's disease  
    Year of PhD dissertation: 2018  
    Name of Supervisor: Prof. Fernanda Borges  
    International hosting institution: University of Santiago de Compostela (Spain)  
    Name of the host supervisor: Prof. Eugenio Uriarte  


Reis Joana Alexandra Costa

University of Porto (Portugal)

     
  Fernandes Carlos   Title of the PhD thesis: Single and multi - target agents for neurodegenerative diseases based on the chromone scaffold  
    Year of PhD dissertation: 2018  
    Name of Supervisor: Prof. Fernanda Borges  
    International hosting institution: University of Pavia (Italy)  
    Name of the host supervisor: Prof. Claudia Binda  


Romeo, Isabella

Universita' degli Studi 'Magna Graecia' di Catanzaro (Italy)

     
  Romeo Isabella   Title of the PhD thesis: Computational studies on antiviral targets: drug resistance mechanisms and rational drug design  
    Year of PhD dissertation: 2018  
    Name of Supervisor: Dr. Anna Artese  
    International hosting institution: Yale University, New Haven, Connecticut (USA)  
    Name of the host supervisor: Prof. William Jorgensen  


Talarico, Carmine

Universita' degli Studi 'Magna Graecia' di Catanzaro (Italy)

     
  Talarico Carmine   Title of the PhD thesis: Evaluation and application of molecular modeling algorithms to relevant pharmaceutical targets  
    Year of PhD dissertation: 2018  
    Name of Supervisor: Prof. Francesco Ortuso  
    International hosting institution: Molecular Discovery Ltd. (UK)  
    Name of the host supervisor: Dr. Simon Cross  


7th Meeting of the Paul Ehrlich MedChem Euro-PhD Network, 25-27 August 2017, Vienna (Austria)

Desantis, Jenny

Universita' degli Studi di Perugia, (Italy)

     
  Desantis Jenny   Title of the PhD thesis: Cycloheptathiophene-3-carboxamide and triazolopyrimidine scaffolds for inhibiting essential targets within HIV-1 and Influenza virus replicative cycle  
    Year of PhD dissertation: 2017  
    Name of Supervisor: Dr. Oriana Tabarrini  
    International hosting institution: Instituto de Quimica Medica - Consejo Superior de investigaciones Cientificas (IQM-CSIC), Madrid (Spain)  
    Name of the host supervisor: Prof. Maria Jose' Camarasa  


Fonseca, Andre'

University of Porto (Portugal)

     
  Fonseca Andre   Title of the PhD thesis: Discovery of target directed drugs for neurodegenerative diseases based on the benzopyrone scaffold  
    Year of PhD dissertation: 2017  
    Name of Supervisor: Prof. Dra. Fernanda Borges  
    International hosting institution: Neuroscience Medicinal Chemistry Department at Janssen Research and Development in Beerse (Belgium)  
    Name of the host supervisor: Prof. Dr. Eugenio Uriarte  


6th Meeting of the Paul Ehrlich MedChem Euro-PhD Network, 18-20 November 2016, Budapest (Hungary)

Bianco, Giulia

Universita' degli studi di Cagliari (Italy)

     
  Bianco Giulia   Title of the PhD thesis: Structure-based approaches applied to the study of pharmaceutical relevant targets  
    Year of PhD dissertation: 2016  
    Name of Supervisor: Dr. Simona Distinto  
    International hosting institution: Laboratory of Molecular Modelling, department of biomedical sciences, University of Alcala', Alcala' de Henares, Madrid (Spain)  
    Name of the host supervisor: Dr. Federico Gago  


Ciordia Jimenez, Myriam

San Pablo CEU, Madrid (Spain)

     
  Fonseca Andre   Title of the PhD thesis: Novel Amidine-Class Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors for the Treatment of Alzheimer's Disease  
    Year of PhD dissertation: 2016  
    Name of Supervisor: Prof. Dr. Beatriz de Pascual-Teresa and Dr. Andres A. Trabanco  
    International hosting institution: Neuroscience Medicinal Chemistry Department at Janssen Research and Development in Beerse (Belgium)  
    Name of the host supervisor: Dr. Frederik Rombouts  


Rocca, Roberta

Universita' degli Studi 'Magna Graecia' di Catanzaro (Italy)

     
  Rocca, Roberta   Title of the PhD thesis: G-Quadruplex folds as innovative conformational target for in-silico-driven hit identification of novel bioactive agents  
    Year of PhD dissertation: 2016  
    Name of Supervisor: Prof. Stefano Alcaro  
    International hosting institution: ETH Zurich, Department of Chemistry and Applied Biosciences, USI Campus Lugano (Switzerland)  
    Name of the host supervisor: Prof. Michele Parrinello  


Silva, Tiago

University of Porto (Portugal)

     
  Silva, Tiago   Title of the PhD thesis: Hydroxycinnamic acid, a valid scaffold for the development of CNS multitarget drugs. Synthesis, pharmacological and toxicological studies  
    Year of PhD dissertation: 2016  
    Name of Supervisor: Prof. Dr. Fernanda Borges  
    International hosting institution: University of Santiago de Compostela (Spain)  
    Name of the host supervisor: Prof. Dr. Eugenio Uriarte  


Teixeira, Jose'

University of Porto (Portugal)

     
  Teixeira, José   Title of the PhD thesis: Targeting dietary antioxidants to mitochondria: regulating mitochondrial radical production and redox signaling to improve human health  
    Year of PhD dissertation: 2016  
    Name of Supervisor: Prof. Fernanda Borges  
    International hosting institution: Radboud University, Nijmegen (Netherlands)  
    Name of the host supervisor: Dr. Werner Koopman  


5th Meeting of the Paul Ehrlich MedChem Euro-PhD Network, 3-5 July 2015, Kracow (Poland)

Di Vita, Gloria

Universita' degli Studi di Palermo (Italy)

     
  Di Vita, Gloria   Title of the PhD thesis: Synthesis and antiproliferative activity of thiazolyl-bis-pyrrolo[2,3-b]pyridines, indolyl-thiazolyl-pyrrolo[2,3-b]pyridines and indolyl-thiazolyl-pyrrolo[2,3-c]pyridines, nortopsentin analogues  
    Year of PhD dissertation: 2015  
    Name of Supervisor: Prof. G. Cirrincione  
    International hosting institution: UCL, School of Pharmacy, London (UK)  
    Name of the host supervisor: Prof. Steven Neidle  


Szalaj, Natalia

Jagellonian University (Poland)

     
  Szalaj Natalia   Title of the PhD thesis: Synthesis and biological evaluation of a second generation 1,2,3-triazole derivatives as potential anti-Alzheimer's compounds targeting monoamine oxidase B  
    Year of PhD dissertation: 2015  
    Name of Supervisor: Prof. Dr hab. Barbara Malawska  
    International hosting institution: University of Barcelona (Spain)  
    Name of the host supervisor: Dr. Diego Munoz-Torrero  


4th Meeting of the Paul Ehrlich MedChem Euro-PhD Network, 20-22 June 2014, Hradec Kralove', Prague (Czech Republic)

Gaspar, Alexandra

University of Porto (Portugal)

     
  Gaspar Alexandra   Title of the PhD thesis: Chromone: a valid scaffold in medicinal chemistry  
    Year of PhD dissertation: 2014  
    Name of Supervisor: Prof. Fernanda Borges  
    International hosting institution: Universita' degli Studi 'Magna Graecia' di Catanzaro (Italy)  
    Name of the host supervisor: Prof. Stefano Alcaro  


Moraca, Federica

Universita' degli Studi 'Magna Graecia' di Catanzaro (Italy)

     
  Moraca Federica   Title of the PhD thesis: Traditional and enhanced computational approaches for the rational discovery of novel DNA G-quadruplex stabilizing agents  
    Year of PhD dissertation: 2014  
    Name of Supervisor: Prof. Stefano Alcaro  
    International hosting institution: ETH Zurich, Department of Chemistry and Applied Biosciences, USI Campus Lugano (Switzerland)  
    Name of the host supervisor: Prof. Michele Parrinello  


Morreale, Francesca

Universita' degli studi di Messina (Italy)

     
  Morreale, Francesca   Title of the PhD thesis: New challenges in drug discovery: targeting protein-protein interactions  
    Year of PhD dissertation: 2014  
    Name of Supervisor: Prof. Alba Chimirri  
    International hosting institution: University of Cambridge, University of Dundee (UK)  
    Name of the host supervisor: Dr. Alessio Ciulli  


3th Meeting of the Paul Ehrlich MedChem Euro-PhD Network, 27-29 september 2013, Santa Margherita di Pula, Cagliari (Italy)

Brvar, Matjaz

University of Ljubljana (Slovenia)

     
  Brvar Matjaz   Title of the PhD thesis: Structure-based design of DNA gyrase B inhibitors  
    Year of PhD dissertation: 2013  
    Name of Supervisor: Prof. Tomaa Solmajer  
    International hosting institution: University of Lund, Lund (Sweden)  
    Name of the host supervisor: Prof. Salam Al-Karadaghi  


Meleddu, Rita

Universita' degli studi di Cagliari (Italy)

     
  Meleddu, Rita   Title of the PhD thesis: Synthesis of different series of small molecules targeting HIV-1 RT, Candida albicans, MAO and G-quadruplex  
    Year of PhD dissertation: 2013  
    Name of Supervisor: Prof. Elias Maccioni  
    International hosting institution: Semmelweis University, Budapest (Hungary)  
    Name of the host supervisor: Prof. Peter Matyus  


2th Meeting of the Paul Ehrlich MedChem Euro-PhD Network, 9-11 September 2012, Ljubljana (Slovenia)

Buemi, Maria Rosa

Universita' degli studi di Messina (Italy)

     
  Buemi Maria Rosa   Title of the PhD thesis: Rational design and synthesis of new GluN2B/NMDA receptor ligands as neuroprotective agents  
    Year of PhD dissertation: 2012  
    Name of Supervisor: Prof. Alba Chimirri  
    International hosting institution: University of Alcala',
Alcala' de Henares (Spain)
 
    Name of the host supervisor: Prof. Julio Alvarez-Builla  


Parrino, Barbara

Universita' degli studi di Palermo, Italy

     
  Barbara Parrino   Title of the PhD thesis: Synthesis and antitumor activity of new tetracyclic systems containing the pirrole ring  
    Year of PhD dissertation: 2012  
    Name of Supervisor: Prof. G. Cirrincione  
    International hosting institution: Semmelweis University, Budapest (Hungary)  
    Name of the host supervisor: Prof. Peter Matyus  

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