PhD Awarded
The first Paul Ehrlich MedChem Euro-PhD certificate was awarded in 2012 at the Network meeting in Ljubljana and since then altogether 42 certificates were awarded to superb doctoral students who obtained their national PhD degree in medicinal chemistry.
PhDs awarded are listed by year meeting.XI Meeting of the Paul Ehrlich Euro-PhD Network - #PEVM2022, July 14th-16th, 2022 - Barcelona
Barreca, Marilia
University of Palermo (Italy)
Title of the PhD thesis: [1,2]oxazole derivatives: synthesis and biological evaluation against multiple malignant cell types Year of PhD dissertation: 2021 Name of Supervisor: Prof. Paola BArraja International hosting institution: Institute of Oncology Research (IOR), Bellinzona
(Switzerland)Name of the host supervisor: Prof. Francesco Bertoni
Coricello, Adriana
Universita' degli Studi 'Magna Graecia' di Catanzaro (Italy)
Title of the PhD thesis: Natural products in drug discovery. In silico approaches for the detection of new hits against unexplored molecular targets Year of PhD dissertation: 2022 Name of Supervisor: Prof. Stefano Alcaro International hosting institution: Cardiff University
(Galles)Name of the host supervisor: Prof. Nigel Richards
Mirabile, Salvatore
University of Messina (Italy)
Title of the PhD thesis: Structure- and Ligand-based Optimization of Fragment Binding Tyrosinase from Agaricus bisporus to Develop Anti-Melanogenic Agents Year of PhD dissertation: 2022 Name of Supervisor: Prof. Rosaria Gitto International hosting institution: University of Vienna
(Austria)Name of the host supervisor: Prof. Vittorio Pace
Nizi, Maria Giulia
University of Perugia (Italy)
Title of the PhD thesis: Discovery of potent and selective PARP inhibitors as valuable pharmacological tools and next generation anticancer agents Year of PhD dissertation: 2022 Name of Supervisor: Prof. Oriana Tabarrini International hosting institution: University of Oulu
(Finland)Name of the host supervisor: Prof. Lari Lehtio
Rullo, Mariagrazia
University of Bari "Aldo Moro" (Italy)
Title of the PhD thesis: Development of MAO-B centered Multitarget ligands against Neurodegenerative Disorders Year of PhD dissertation: 2022 Name of Supervisor: Prof. Cosimo Damiano Altomare International hosting institution: University of Umea (Sweden) Name of the host supervisor: Prof. Anna Linusson Paul Ehrlich Euro-PhD Network Virtual Meeting 2021 - #PEVM2021, July 26th-28th, 2021th-16th, 2022
Ambrosio, Francesca Alessandra
Universita' degli Studi 'Magna Graecia' di Catanzaro (Italy)
Title of the PhD thesis: Molecular Modeling studies on antiviral targets: drug resistance mechanisms and rational drug design Year of PhD dissertation: 2019 Name of Supervisor: Prof. Anna Artese International hosting institution: Scripps Research Institute
La Jolla, CA (USA)Name of the host supervisor: Prof. Stefano Forli
Bouz, Ghada
Charles University (Czech Republic)
Title of the PhD thesis: Pyrazinecarboxamide derivatives as potential antimicrobials Year of PhD dissertation: 2020 Name of Supervisor: Prof. Martin Dolezal International hosting institution: San Pablo University (CEU) Madrid (Spain) Name of the host supervisor: Prof. Ana Ramos
Ceramella, Jessica
University of Calabria (Italy)
Title of the PhD thesis: Design and biological evaluation of new anticancer agents vehicled in innovative pharmaceutical matrices Year of PhD dissertation: 2020 Name of Supervisor: Prof. Maria Stefania Sinicropi
and Prof. Domenico GabrieleInternational hosting institution: Centre d'etudes et de recherche sur le medicament de Normandie (CERMN),
Universite' de Caen Normandie (France)Name of the host supervisor: Prof. Aurelie Malzert-Freon
and Dr. Anne-Claire Groo
Chavarria, Daniel
University of Porto (Portugal)
Title of the PhD thesis: Development of new chemical entities based on natural scaffolds with therapeutic potential towards age related disorders Year of PhD dissertation: 2020 Name of Supervisor: Prof. Maria Fernanda Martins Borges International hosting institution: Faculty of Pharmacy of the University of Santiago de Compostela Name of the host supervisor: Prof. Dr. Eugenio Uriarte Villares
Di Geronimo Quintero, Bruno
Universidad San Pablo-CEU (Spain)
Title of the PhD thesis: Computer-aided Drug Design based on Phosphatases (PTPRZ, PTPRGamma, PTP1B), Kinases (CK2)and Histone Deacetylases (HDAC1, HDAC6) as drug targets Year of PhD dissertation: 2020 Name of Supervisor: Prof. Beatriz de Pascual-Teresa Fernandez International hosting institution: Institute of Organic Chemistry and Biochemistry (IOCB), Prague (Czech Republic) Name of the host supervisor: Dr. Lubomir Rulisek
Mancuso, Francesca
University of Messina (Italy)
Title of the PhD thesis: Targeting Carbonic Anhydrases (CAs): Rational Design, Synthesis, Structural Studies and Biochemical Evaluation Year of PhD dissertation: 2021 Name of Supervisor: Prof. Rosaria Gitto International hosting institution: Institute of Organic Chemistry and Biochemistry of the CAS, Prague (Czech Republic) Name of the host supervisor: Dr. Milan Vrabel
Marin, Javier Garcia
Universidad de Alcala' (Spain)
Title of the PhD thesis: Strategies against chronic kidney disease: new modulators of PTP1B and ILK Year of PhD dissertation: 2020 Name of Supervisor: Prof. Juan Jose' Vaquero
and Prof. Ramon AlajarinInternational hosting institution: School of Chemistry, Department of Theoretical Chemistry, University of Bristol (UK) Name of the host supervisor: Prof. Adrian J. Mulholland
Mesiti, Francesco
Universita' degli Studi 'Magna Graecia' di Catanzaro (Italy)
Title of the PhD thesis: Mapping the chromone-3-phenylcarboxamide pharmacophore: structure-activity-toxicity and efflux trasport studies Year of PhD dissertation: 2020 Name of Supervisor: Prof. Stefano Alcaro International hosting institution: FCUP Faculdade de Ciencia, Universidade do Porto (Portugal) Name of the host supervisor: Prof. Maria Fernanda Martins Borges
Szczepanska, Katarzyna
Jagiellonian University Medical College (Poland)
Title of the PhD thesis: The search for novel histamine H3 receptor ligands in the group of piperazine derivatives Year of PhD dissertation: 2020 Name of Supervisor: Prof. Katarzyna Kiec-Kononowicz International hosting institution: University of Regensburg (Germany) Name of the host supervisor: Prof. Steffen Pockes
Vittorio, Serena
University of Messina (Italy)
Title of the PhD thesis: Study and design of modulators of protein-protein interactions implicated in tumor and neurodegenerative diseases Year of PhD dissertation: 2021 Name of Supervisor: Prof. Laura De Luca International hosting institution: University of Vienna (Austria) Name of the host supervisor: Prof. Thierry Langer
9th Meeting of the Paul Ehrlich MedChem Euro-PhD Network, 13-15 June 2019, Catanzaro (Italy)
Bagetta, Donatella
Universita' degli Studi 'Magna Graecia' di Catanzaro (Italy)
Title of the PhD thesis: Computational studies on MAO-B and AChE inhibitors as potential anti-Parkinson's and anti-Alzheimer's agents Year of PhD dissertation: 2019 Name of Supervisor: Prof. Francesco Ortuso International hosting institution: University of Vienna (Austria) Name of the host supervisor: Prof. Thierry Langer
Benfeito, Sofia
University of Porto (Portugal)
Title of the PhD thesis: Design and development of multi-target agents for neurodegenerative diseases Year of PhD dissertation: 2019 Name of Supervisor: Prof. Fernanda Borges International hosting institution: Faculty of Pharmacy of Santiago de Compostela (Spain) Name of the host supervisor: Prof. Eugenio Uriarte
Felicetti, Tommaso
University of Perugia (Italy)
Title of the PhD thesis: Quinoline-based efflux inhibitors as antimicrobial resistance breakers (ARB) Year of PhD dissertation: 2019 Name of Supervisor: Prof. Violetta Cecchetti and Prof. Stefano Sabatini International hosting institution: University of Groningen (Netherlands) Name of the host supervisor: Prof. Anna K.H. Hirsch
Fernandes, Carlos
University of Porto (Portugal)
Title of the PhD thesis: Development of PEGylated platforms to overcome blood-brain barrier constraints in neurodegenerative therapy Year of PhD dissertation: 2019 Name of Supervisor: Prof. Fernanda Borges International hosting institution: Faculty of Pharmacy of Santiago de Compostela (Spain) Name of the host supervisor: Prof. Eugenio Uriarte
Ielo, Laura
University of Messina (Italy)
Title of the PhD thesis: Identification of New Tyrosinase Inhibitors via Computational Studies, Synthesis and Structural Characterization Year of PhD dissertation: 2019 Name of Supervisor: Prof. Laura De Luca International hosting institution: University of Vienna (Austria) Name of the host supervisor: Prof. Vittorio Pace
Lupia, Antonio
Universita' degli Studi 'Magna Graecia' di Catanzaro (Italy)
Title of the PhD thesis: Molecular modelling of the epitopes recognized by neoplastic B-cells in Chronic Lymphocytic Leukemia Year of PhD dissertation: 2019 Name of Supervisor: Prof. Ileana Quinto International hosting institution: Institute of Oncology Research - IOR, Bellinzona (Switzerland) Name of the host supervisor: Dr. Eugenio Gaudio
8th Meeting of the Paul Ehrlich MedChem Euro-PhD Network, 12-14 July 2018, Porto (Portugal)
Astolfi, Andrea
University of Perugia (Italy)
Title of the PhD thesis: Computational Modeling and Inhibitor Design of p38 MAPK Year of PhD dissertation: 2018 Name of Supervisor: Prof. Maria Letizia Barreca and Prof. Violetta Cecchetti International hosting institution: Institute of Structural and Molecular Biology, London (UK) Name of the host supervisor: Prof. Francesco Luigi Gervasio, PhD
Castoldi, Laura
University of Vienna (Austria)
Title of the PhD thesis: Organic Synthesis with Lithium Carbenoids at the Helm: Mechanistic Aspects and Applications in Synthetic Medicinal Chemistry Year of PhD dissertation: 2018 Name of Supervisor: Dr. Vittorio Pace and Prof. Wolfgang Holzer International hosting institution: Complutense University of Madrid (Spain) Name of the host supervisor: Prof. Andres R Alcantara, PhD
Oliveira, Ana Catarina Gomes
University of Porto (Portugal)
Title of the PhD thesis: Benzoic acid as a valid scaffold for the development of dual- target directed drugs for Alzheimer's disease Year of PhD dissertation: 2018 Name of Supervisor: Prof. Fernanda Borges International hosting institution: University of Santiago de Compostela (Spain) Name of the host supervisor: Prof. Eugenio Uriarte
Reis Joana Alexandra Costa
University of Porto (Portugal)
Title of the PhD thesis: Single and multi - target agents for neurodegenerative diseases based on the chromone scaffold Year of PhD dissertation: 2018 Name of Supervisor: Prof. Fernanda Borges International hosting institution: University of Pavia (Italy) Name of the host supervisor: Prof. Claudia Binda
Romeo, Isabella
Universita' degli Studi 'Magna Graecia' di Catanzaro (Italy)
Title of the PhD thesis: Computational studies on antiviral targets: drug resistance mechanisms and rational drug design Year of PhD dissertation: 2018 Name of Supervisor: Dr. Anna Artese International hosting institution: Yale University, New Haven, Connecticut (USA) Name of the host supervisor: Prof. William Jorgensen
Talarico, Carmine
Universita' degli Studi 'Magna Graecia' di Catanzaro (Italy)
Title of the PhD thesis: Evaluation and application of molecular modeling algorithms to relevant pharmaceutical targets Year of PhD dissertation: 2018 Name of Supervisor: Prof. Francesco Ortuso International hosting institution: Molecular Discovery Ltd. (UK) Name of the host supervisor: Dr. Simon Cross
7th Meeting of the Paul Ehrlich MedChem Euro-PhD Network, 25-27 August 2017, Vienna (Austria)
Desantis, Jenny
Universita' degli Studi di Perugia, (Italy)
Title of the PhD thesis: Cycloheptathiophene-3-carboxamide and triazolopyrimidine scaffolds for inhibiting essential targets within HIV-1 and Influenza virus replicative cycle Year of PhD dissertation: 2017 Name of Supervisor: Dr. Oriana Tabarrini International hosting institution: Instituto de Quimica Medica - Consejo Superior de investigaciones Cientificas (IQM-CSIC), Madrid (Spain) Name of the host supervisor: Prof. Maria Jose' Camarasa
Fonseca, Andre'
University of Porto (Portugal)
Title of the PhD thesis: Discovery of target directed drugs for neurodegenerative diseases based on the benzopyrone scaffold Year of PhD dissertation: 2017 Name of Supervisor: Prof. Dra. Fernanda Borges International hosting institution: Neuroscience Medicinal Chemistry Department at Janssen Research and Development in Beerse (Belgium) Name of the host supervisor: Prof. Dr. Eugenio Uriarte
6th Meeting of the Paul Ehrlich MedChem Euro-PhD Network, 18-20 November 2016, Budapest (Hungary)
Bianco, Giulia
Universita' degli studi di Cagliari (Italy)
Title of the PhD thesis: Structure-based approaches applied to the study of pharmaceutical relevant targets Year of PhD dissertation: 2016 Name of Supervisor: Dr. Simona Distinto International hosting institution: Laboratory of Molecular Modelling, department of biomedical sciences, University of Alcala', Alcala' de Henares, Madrid (Spain) Name of the host supervisor: Dr. Federico Gago
Ciordia Jimenez, Myriam
San Pablo CEU, Madrid (Spain)
Title of the PhD thesis: Novel Amidine-Class Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors for the Treatment of Alzheimer's Disease Year of PhD dissertation: 2016 Name of Supervisor: Prof. Dr. Beatriz de Pascual-Teresa and Dr. Andres A. Trabanco International hosting institution: Neuroscience Medicinal Chemistry Department at Janssen Research and Development in Beerse (Belgium) Name of the host supervisor: Dr. Frederik Rombouts
Rocca, Roberta
Universita' degli Studi 'Magna Graecia' di Catanzaro (Italy)
Title of the PhD thesis: G-Quadruplex folds as innovative conformational target for in-silico-driven hit identification of novel bioactive agents Year of PhD dissertation: 2016 Name of Supervisor: Prof. Stefano Alcaro International hosting institution: ETH Zurich, Department of Chemistry and Applied Biosciences, USI Campus Lugano (Switzerland) Name of the host supervisor: Prof. Michele Parrinello
Silva, Tiago
University of Porto (Portugal)
Title of the PhD thesis: Hydroxycinnamic acid, a valid scaffold for the development of CNS multitarget drugs. Synthesis, pharmacological and toxicological studies Year of PhD dissertation: 2016 Name of Supervisor: Prof. Dr. Fernanda Borges International hosting institution: University of Santiago de Compostela (Spain) Name of the host supervisor: Prof. Dr. Eugenio Uriarte
Teixeira, Jose'
University of Porto (Portugal)
Title of the PhD thesis: Targeting dietary antioxidants to mitochondria: regulating mitochondrial radical production and redox signaling to improve human health Year of PhD dissertation: 2016 Name of Supervisor: Prof. Fernanda Borges International hosting institution: Radboud University, Nijmegen (Netherlands) Name of the host supervisor: Dr. Werner Koopman
5th Meeting of the Paul Ehrlich MedChem Euro-PhD Network, 3-5 July 2015, Kracow (Poland)
Di Vita, Gloria
Universita' degli Studi di Palermo (Italy)
Title of the PhD thesis: Synthesis and antiproliferative activity of thiazolyl-bis-pyrrolo[2,3-b]pyridines, indolyl-thiazolyl-pyrrolo[2,3-b]pyridines and indolyl-thiazolyl-pyrrolo[2,3-c]pyridines, nortopsentin analogues Year of PhD dissertation: 2015 Name of Supervisor: Prof. G. Cirrincione International hosting institution: UCL, School of Pharmacy, London (UK) Name of the host supervisor: Prof. Steven Neidle
Szalaj, Natalia
Jagellonian University (Poland)
Title of the PhD thesis: Synthesis and biological evaluation of a second generation 1,2,3-triazole derivatives as potential anti-Alzheimer's compounds targeting monoamine oxidase B Year of PhD dissertation: 2015 Name of Supervisor: Prof. Dr hab. Barbara Malawska International hosting institution: University of Barcelona (Spain) Name of the host supervisor: Dr. Diego Munoz-Torrero
4th Meeting of the Paul Ehrlich MedChem Euro-PhD Network, 20-22 June 2014, Hradec Kralove', Prague (Czech Republic)
Gaspar, Alexandra
University of Porto (Portugal)
Title of the PhD thesis: Chromone: a valid scaffold in medicinal chemistry Year of PhD dissertation: 2014 Name of Supervisor: Prof. Fernanda Borges International hosting institution: Universita' degli Studi 'Magna Graecia' di Catanzaro (Italy) Name of the host supervisor: Prof. Stefano Alcaro
Moraca, Federica
Universita' degli Studi 'Magna Graecia' di Catanzaro (Italy)
Title of the PhD thesis: Traditional and enhanced computational approaches for the rational discovery of novel DNA G-quadruplex stabilizing agents Year of PhD dissertation: 2014 Name of Supervisor: Prof. Stefano Alcaro International hosting institution: ETH Zurich, Department of Chemistry and Applied Biosciences, USI Campus Lugano (Switzerland) Name of the host supervisor: Prof. Michele Parrinello
Morreale, Francesca
Universita' degli studi di Messina (Italy)
Title of the PhD thesis: New challenges in drug discovery: targeting protein-protein interactions Year of PhD dissertation: 2014 Name of Supervisor: Prof. Alba Chimirri International hosting institution: University of Cambridge, University of Dundee (UK) Name of the host supervisor: Dr. Alessio Ciulli
3th Meeting of the Paul Ehrlich MedChem Euro-PhD Network, 27-29 september 2013, Santa Margherita di Pula, Cagliari (Italy)
Brvar, Matjaz
University of Ljubljana (Slovenia)
Title of the PhD thesis: Structure-based design of DNA gyrase B inhibitors Year of PhD dissertation: 2013 Name of Supervisor: Prof. Tomaa Solmajer International hosting institution: University of Lund, Lund (Sweden) Name of the host supervisor: Prof. Salam Al-Karadaghi
Meleddu, Rita
Universita' degli studi di Cagliari (Italy)
Title of the PhD thesis: Synthesis of different series of small molecules targeting HIV-1 RT, Candida albicans, MAO and G-quadruplex Year of PhD dissertation: 2013 Name of Supervisor: Prof. Elias Maccioni International hosting institution: Semmelweis University, Budapest (Hungary) Name of the host supervisor: Prof. Peter Matyus
2th Meeting of the Paul Ehrlich MedChem Euro-PhD Network, 9-11 September 2012, Ljubljana (Slovenia)
Buemi, Maria Rosa
Universita' degli studi di Messina (Italy)
Title of the PhD thesis: Rational design and synthesis of new GluN2B/NMDA receptor ligands as neuroprotective agents Year of PhD dissertation: 2012 Name of Supervisor: Prof. Alba Chimirri International hosting institution: University of Alcala',
Alcala' de Henares (Spain)Name of the host supervisor: Prof. Julio Alvarez-Builla
Parrino, Barbara
Universita' degli studi di Palermo, Italy
Title of the PhD thesis: Synthesis and antitumor activity of new tetracyclic systems containing the pirrole ring Year of PhD dissertation: 2012 Name of Supervisor: Prof. G. Cirrincione International hosting institution: Semmelweis University, Budapest (Hungary) Name of the host supervisor: Prof. Peter Matyus
